Assuming high conviction and don't care about risk, any reason to not go 2x 3x leveraged?

Assuming one have super high conviction in a stock direction and doesn't care about risk, is there a reason *not* to go 2x 3x 4x leveraged?

The only downside is if it goes the other direction, you lose faster, right? Any other disadvantages?

It's not like an option where if it goes the other direction, it immediately goes -100% in a couple days