I'm receiving 140k when I am 25 from my grandpa. What's the best way to invest it for retirement? (I am Canadian)

In half a year I will be 25. I am thinking of splitting the money as 110k for retirement, 10k for savings/emergency (will not touch) 10k for a new cheap vehicle plus insurance, and 10k for fun.

In terms of the 110k, will just shoving it into The s&p 500 and forgetting about it until I'm 60 be a pretty good bet? I can put almost 50k into a TFSA investment portfolio that will not be taxed when I take out the money from the market and the other 50k will be taxed 25 percent I believe. I also plan to add 5k a year on top. This a good start to a plan?